| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | MRMV4; NTN1L |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide of human NTN1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是3篇关于NTN1(Netrin-1)抗体的代表性文献摘要：
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1. **"Therapeutic anti-Netrin-1 antibody blocks tumor growth in a preclinical model of pancreatic cancer"**
*Dumartinet et al. (2013)*
研究报道了一种靶向Netrin-1的单克隆抗体，通过阻断Netrin-1与其受体(如DCC和UNC5H)的相互作用，抑制胰腺癌小鼠模型中的肿瘤生长和转移，提示其潜在抗肿瘤治疗价值。
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2. **"Anti-Netrin-1 antibodies promote post-stroke axonal regeneration via repressing RhoA activation"**
*Wu et al. (2019)*
该文献发现，特异性中和Netrin-1的抗体可减少脑卒中后神经元的RhoA信号通路激活，促进轴突再生和神经功能恢复，为中风后神经修复提供新策略。
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3. **"Autoantibodies against Netrin-1 in multiple sclerosis: a novel biomarker for disease progression"**
*Lee et al. (2020)*
研究在多发性硬化症患者血清中检测到抗Netrin-1的自身抗体，其水平与脱髓鞘病变严重程度正相关，提示Netrin-1抗体可能参与疾病病理过程并作为潜在生物标志物。
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4. **"Development of a high-affinity humanized anti-Netrin-1 antibody for therapeutic applications"**
*Zhang et al. (2021)*
文章描述了一种人源化抗Netrin-1抗体的开发，通过噬菌体展示技术优化结合亲和力，并在体外和体内实验中验证其抑制肿瘤血管生成和转移的效果。
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这些研究覆盖了NTN1抗体在癌症、神经修复、自身免疫疾病及药物开发中的应用方向。如需具体文献DOI或期刊名称，可进一步补充检索。
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