Rabbit Polyclonal MYBPC1 Antibody

The MYBPC1 antibody targets Myosin Binding Protein C1 (MYBPC1), a key regulatory protein expressed predominantly in skeletal muscle. Encoded by the MYBPC1 gene located on chromosome 12 in humans, MYBPC1 is part of the sarcomere’s thick filament and plays a critical role in modulating muscle contraction by interacting with myosin and titin. It is specifically enriched in fast-twitch muscle fibers, influencing contractile kinetics and mechanical stability. MYBPC1 antibodies are widely used in research to study its expression, localization, and function in muscle physiology. These antibodies are essential tools for techniques like Western blotting, immunohistochemistry, and immunofluorescence, aiding in investigations of neuromuscular disorders, such as distal arthrogryposis and myopathies linked to MYBPC1 mutations. Additionally, they help elucidate MYBPC1's role in developmental biology and its interactions within the sarcomeric network. Studies using MYBPC1 antibodies have also explored its conservation across species, highlighting its evolutionary significance in muscle architecture. As a biomarker, MYBPC1 is of interest in both diagnostic research and therapeutic development for muscle-related diseases. The antibody’s specificity and reliability make it a valuable resource for advancing understanding of skeletal muscle regulation and disease mechanisms.