| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/30-1/150 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | RBP4 |
| Entrez GeneID | 5950 |
| clone | 4C2 |
| WB Predicted band size | 23kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human RBP expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
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以下是关于GPBPBP1L1抗体的虚构参考文献示例(请注意，实际文献可能需要通过学术数据库核实)：
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1. **"GPBPBP1L1 Antibody Validation in Epithelial Carcinoma Studies"**
*Authors: Zhang et al.*
**摘要**：本研究开发并验证了一种针对GPBPBP1L1蛋白的高特异性单克隆抗体，用于检测其在肺癌和结肠癌组织中的异常表达，证实其与肿瘤进展的相关性。
2. **"Immunohistochemical Analysis of GPBPBP1L1 in Cardiac Tissues"**
*Authors: Martinez et al.*
**摘要**：利用GPBPBP1L1多克隆抗体进行心脏组织免疫组化分析，揭示其在心肌细胞中的定位及与心肌病相关的表达变化。
3. **"GPBPBP1L1 Antibody Application in Protein Interaction Profiling"**
*Authors: Kim et al.*
**摘要**：通过免疫共沉淀(Co-IP)技术结合GPBPBP1L1抗体，鉴定该蛋白与细胞骨架调控因子的相互作用，为信号通路研究提供工具。
4. **"Commercial GPBPBP1L1 Antibody Comparative Study"**
*Authors: Wang et al.*
**摘要**：评估不同商业来源的GPBPBP1L1抗体的灵敏度和特异性，提出优化Western blot和流式细胞术检测方案的建议。
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**注意**：以上内容为示例，实际文献需通过PubMed、Google Scholar等平台检索确认。若研究领域较新或名称有误，建议核查基因别名(如GPBP1-L1)或联系抗体供应商获取技术文档。
The GPBP1L1 (GC-rich promoter binding protein 1-like 1) antibody is a tool used to detect and study the GPBP1L1 protein, a lesser-characterized member of the GPBP family. GPBP1L1 is believed to function as a transcriptional regulator, potentially binding to GC-rich promoter regions to modulate gene expression. While its exact biological roles remain under investigation, studies suggest involvement in cellular processes such as differentiation, proliferation, and stress responses. It shares structural homology with GPBP1 (also known as C9orf96), a protein implicated in immune regulation and autoimmune diseases.
The GPBP1L1 antibody is primarily utilized in research applications like Western blotting, immunohistochemistry, and immunofluorescence to determine protein expression levels, subcellular localization (likely nuclear or cytoplasmic), and tissue distribution. Its development often involves immunizing hosts with synthetic peptides or recombinant protein fragments unique to GPBP1L1. Recent studies have explored its potential relevance in cancer, where altered expression may correlate with tumor progression, though mechanistic insights are still emerging. Validation of this antibody includes specificity tests using knockout cell lines or siRNA knockdown to ensure minimal cross-reactivity with homologous proteins like GPBP1L. As GPBP1L1's functional pathways are clarified, this antibody will remain critical for unraveling its contributions to both normal physiology and disease.
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