| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | NET46 |
| WB Predicted band size | 62 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human SLC22A24 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于SLC22A24抗体的3篇假设性参考文献示例(注：SLC22A24相关研究较少，实际文献可能需要通过数据库检索验证)：
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1. **文献名称**：*"Characterization of a Novel Polyclonal Antibody for SLC22A24 in Human Renal Tissue"*
**作者**：Smith J, et al.
**摘要**：本研究开发并验证了一种针对SLC22A24蛋白的多克隆抗体，通过免疫组化及Western blot证实其在人肾脏组织中的特异性表达，提示SLC22A24可能在肾脏有机溶质转运中发挥作用。
2. **文献名称**：*"SLC22A24 as a Uremic Toxin Transporter: Insights from Antibody-Based Knockdown Models"*
**作者**：Chen L, et al.
**摘要**：利用抗SLC22A24的siRNA和抗体阻断实验，揭示了该蛋白在肝细胞中对尿毒症毒素(如硫酸对甲酚)的外排功能，为慢性肾病代谢研究提供新靶点。
3. **文献名称**：*"Tissue Distribution and Evolutionary Conservation of SLC22A24: A Comparative Study Using Immunohistochemistry"*
**作者**：Garcia R, et al.
**摘要**：通过跨物种抗体交叉反应实验，发现SLC22A24在哺乳动物肝脏和肠道中高度保守，可能参与胆汁酸或药物代谢产物的跨膜转运。
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**提示**：若需真实文献，建议在PubMed或Google Scholar中检索关键词“SLC22A24 antibody”或“SLC22A24 function”，并筛选涉及抗体开发/应用的实验研究。部分相关研究可能整合在SLC22家族综述中。
The SLC22A24 antibody is a research tool designed to detect and study the solute carrier family 22 member 24 (SLC22A24) protein, a relatively undercharacterized transporter within the SLC22 family. This family encompasses membrane proteins involved in the transport of endogenous compounds, xenobiotics, and drugs across cellular membranes, primarily in excretory organs like the kidney and liver. SLC22A24. though less studied compared to other members (e.g., SLC22A1/OCT1 or SLC22A6/OAT1), is hypothesized to play roles in organic anion/cation transport, potentially influencing drug disposition, detoxification, or metabolic pathways. Its expression patterns, substrate specificity, and physiological relevance remain areas of active investigation.
The SLC22A24 antibody is typically developed for applications such as Western blotting, immunohistochemistry, or immunofluorescence to localize the protein in tissues or assess its expression levels under varying conditions. Its utility lies in elucidating SLC22A24's tissue distribution, regulatory mechanisms, and involvement in disease contexts, such as renal dysfunction, metabolic disorders, or drug resistance. Validation of antibody specificity (e.g., via knockout controls) is critical due to potential cross-reactivity within the SLC22 family. Research using this antibody aims to clarify SLC22A24's biological and pharmacological significance, bridging gaps in understanding solute carrier biology and therapeutic targeting.
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