关键信息
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基因名
C1QTNF1/CTRP1
- 应用
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别名
(G protein-coupled receptor-interacting protein)(GIP)
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种属
Human
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表达系统
E. coli
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标签
N- GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BXJ1
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表达区间
26-281aa
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分子量
56.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
C1QTNF1, also known as CTRP1, is a member of the C1q/TNF-related protein family, which plays a crucial role in various metabolic and physiological processes, particularly in energy homeostasis and inflammation. Research has indicated that CTRP1 is involved in modulating insulin sensitivity and adipogenesis, making it a potential target for addressing metabolic disorders such as obesity and type 2 diabetes. Its structure, characterized by a globular C1q domain and a helical region, enables it to participate in multiple signaling pathways, including those related to metabolic regulation. As a circulating adipokine, CTRP1 has been shown to have protective effects against cardiovascular diseases and to enhance the function of endothelial cells through its interaction with specific receptors. The interest in recombinant CTRP1 protein arises from its therapeutic potential; understanding its mechanisms of action could lead to novel treatment strategies for metabolic syndrome and related diseases. Moreover, investigating the biochemical properties and physiological functions of recombinant CTRP1 may provide insights into its role in systemic metabolism and contribute to the development of biomarker assays for clinical applications. This research highlights the significance of CTRP1 not only in metabolism but also in its potential implications in other physiological contexts, emphasizing the need for further studies to elucidate its full spectrum of biological activities and therapeutic possibilities.
