| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/20-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | KNP-I |
| WB Predicted band size | 28 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human GATD3B |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于GATAD3B抗体的3篇参考文献示例(注：内容为模拟虚构，仅供参考)：
1. **文献名称**: *GATAD3B regulates breast cancer progression through chromatin remodeling*
**作者**: Smith JL, et al.
**摘要**: 本研究利用GATAD3B特异性抗体进行ChIP-seq分析，发现GATAD3B通过结合组蛋白去乙酰化酶复合物调控乳腺癌细胞中关键基因的染色质可及性，促进肿瘤转移。
2. **文献名称**: *Mitochondrial localization and function of GATAD3B revealed by immunofluorescence*
**作者**: Chen R, et al.
**摘要**: 通过GATAD3B抗体的免疫荧光染色，首次证实GATAD3B定位于线粒体内膜，并参与维持线粒体膜电位及能量代谢，为相关代谢疾病研究提供新方向。
3. **文献名称**: *GATAD3B antibody validation in neuronal differentiation models*
**作者**: Wang H, et al.
**摘要**: 该研究通过CRISPR敲除结合Western blot(使用GATAD3B抗体验证蛋白缺失)，证明GATAD3B通过调控神经分化相关转录因子表达，影响皮层神经元发育。
如需真实文献，建议通过PubMed或Google Scholar检索关键词“GATAD3B antibody”或“GATAD3B function”。
The GATD3B antibody is a research tool designed to detect and study the GATD3B (Glycogen Acetyltransferase Domain-Containing Protein 3B), a protein implicated in cellular processes such as post-translational modification and metabolic regulation. GATD3B belongs to the GATD protein family, characterized by conserved acetyltransferase-like domains, though its precise enzymatic activity remains under investigation. It is hypothesized to play a role in glycogen metabolism or protein acetylation, potentially influencing energy homeostasis, cellular stress responses, or epigenetic regulation.
The antibody is typically produced in hosts like rabbits or mice using immunogenic peptides or recombinant protein fragments specific to GATD3B. It is validated for applications such as Western blotting, immunofluorescence, or immunohistochemistry to determine protein expression, localization, and tissue distribution. Studies employing this antibody often focus on metabolic disorders, cancer, or neurodegenerative diseases, where dysregulation of acetylation pathways or glycogen dynamics may contribute to pathogenesis.
Researchers rely on GATD3B antibodies to explore its interaction networks, knockout/knockdown phenotypes, and potential therapeutic relevance. Specificity is confirmed using controls like GATD3B-deficient cell lines or tissues. As research progresses, this antibody aids in unraveling GATD3B's functional significance, bridging gaps in understanding its role in health and disease.
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