| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | ZNF690; Zfp690 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human ZSCAN29 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于ZSCAN29抗体的假设性参考文献示例(请注意，这些文献为模拟内容，实际研究可能需要进一步检索验证)：
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1. **文献名称**：ZSCAN29 Antibody Characterization in Human Pluripotent Stem Cells
**作者**：Smith A, et al.
**摘要**：本研究验证了一种新型ZSCAN29多克隆抗体的特异性，通过Western blot和免疫荧光技术证明其在人胚胎干细胞核内的高表达，提示ZSCAN29可能在多能性维持中发挥作用。
2. **文献名称**：Role of ZSCAN29 in Pancreatic Cancer Progression
**作者**：Li X, et al.
**摘要**：利用ZSCAN29单克隆抗体进行免疫组化分析，发现ZSCAN29在胰腺癌组织中的异常高表达与患者生存率降低相关，可能通过调控Wnt/β-catenin通路促进肿瘤侵袭。
3. **文献名称**：ZSCAN29 Antibody Application in Chromatin Immunoprecipitation (ChIP)
**作者**：Garcia R, et al.
**摘要**：开发了一种适用于ChIP-seq的ZSCAN29兔源抗体，验证其与染色质结合的高效性，揭示ZSCAN29在基因组中靶向调控转座子元件的潜在功能。
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**备注**：
- ZSCAN29作为锌指转录因子家族成员，相关抗体研究可能聚焦于其在发育、癌症或表观遗传调控中的应用。
- 实际文献需通过PubMed、Google Scholar等平台以关键词“ZSCAN29 antibody”或“ZSCAN29 immunohistochemistry”检索确认。
- 若研究较少，可扩展至ZSCAN蛋白家族或交叉引用抗体验证方法学文献(如《Nature Protocols》中的抗体验证指南)。
The ZSCAN29 antibody is a tool used to detect ZSCAN29 (Zinc Finger and SCAN Domain-Containing Protein 29), a transcription factor characterized by its SCAN domain and C2H2-type zinc finger motifs. The SCAN domain mediates protein-protein interactions, often enabling dimerization or recruitment into transcriptional complexes, while zinc fingers facilitate DNA binding, suggesting ZSCAN29's role in regulating gene expression. Although its precise biological functions remain understudied, ZSCAN29 is hypothesized to participate in cellular processes such as differentiation, proliferation, or immune regulation, with potential links to cancer and developmental disorders.
ZSCAN29 antibodies are typically developed in rabbits or mice, targeting specific epitopes within the protein's functional domains. These antibodies are validated for applications like Western blotting, immunofluorescence, or chromatin immunoprecipitation (ChIP) to study ZSCAN29's expression, localization, and DNA-binding activity. Research utilizing these antibodies has explored ZSCAN29's aberrant expression in tumors, its interaction with chromatin modifiers, or its regulatory effects on downstream genes. Commercial ZSCAN29 antibodies often undergo quality checks (e.g., knockout validation) to ensure specificity. Despite limited literature, the antibody serves as a critical reagent for unraveling ZSCAN29's role in transcriptional networks and disease mechanisms, highlighting its growing relevance in molecular and clinical research.
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