| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/30-1/150 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | KOX32 |
| WB Predicted band size | 64 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human ZNF34 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于ZNF34抗体的参考文献示例(注：以下内容为模拟生成，实际文献可能需要通过学术数据库核实)：
1. **文献名称**: "Characterization of the human zinc finger protein ZNF34 and its gene"
**作者**: Jenke, B.H. et al.
**摘要**: 该研究首次克隆了人源ZNF34基因，并制备了针对ZNF34的多克隆抗体，通过免疫印迹和免疫组化验证其在多种组织中的表达模式，提示其在转录调控中的潜在作用。
2. **文献名称**: "Zinc finger proteins in human malignancies: Expression profiling of ZNF34 in colorectal cancer"
**作者**: Miller, A.L. et al.
**摘要**: 研究利用ZNF34特异性抗体分析结直肠癌组织中ZNF34蛋白的表达水平，发现其表达下调可能与肿瘤进展相关，为癌症生物标志物研究提供依据。
3. **文献名称**: "Production and application of monoclonal antibodies against ZNF34 for functional studies"
**作者**: Smith, J.R. et al.
**摘要**: 报道了ZNF34单克隆抗体的开发，验证了其在Western blot、免疫荧光中的高特异性，并用于研究ZNF34在细胞核内的定位及与其他蛋白的相互作用。
4. **文献名称**: "Functional analysis of ZNF34 in transcriptional regulation using RNAi and antibody-based approaches"
**作者**: Lee, S. et al.
**摘要**: 结合RNA干扰和ZNF34抗体，证明ZNF34通过结合特定DNA序列调控下游基因表达，可能参与细胞周期调控，为后续功能研究提供工具。
**注意**：以上文献为示例性质，实际引用时请通过PubMed、Web of Science等平台核实具体信息。若研究领域较窄，建议扩展关键词或联系相关领域作者获取资源。
The ZNF34 antibody is a research tool designed to detect and study Zinc Finger Protein 34 (ZNF34), a member of the zinc finger protein (ZFP) family. Zinc finger proteins are characterized by conserved zinc-binding domains that facilitate DNA, RNA, or protein interactions, playing critical roles in transcriptional regulation, chromatin remodeling, and cellular differentiation. ZNF34. specifically, contains multiple C2H2-type zinc finger motifs, suggesting its involvement in DNA binding and gene expression modulation. While its exact biological functions remain less characterized compared to other ZFPs, ZNF34 is hypothesized to participate in developmental processes, immune responses, or tumorigenesis, based on homologous proteins' roles.
ZNF34 antibodies are typically generated using immunogens derived from recombinant ZNF34 protein fragments or synthetic peptides corresponding to specific epitopes. These antibodies are validated for applications such as Western blotting (WB), immunohistochemistry (IHC), immunofluorescence (IF), or chromatin immunoprecipitation (ChIP). Specificity is confirmed using knockout controls or siRNA-mediated knockdowns. Researchers employ ZNF34 antibodies to explore its expression patterns across tissues, subcellular localization, and interaction networks, as well as its potential dysregulation in diseases like cancer or neurological disorders. Despite limited functional data, ongoing studies aim to elucidate ZNF34's role in cellular pathways, contributing to broader insights into zinc finger protein biology and therapeutic target discovery.
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