| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | PDCR; SDR17C1 |
| WB Predicted band size | 31 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human DECR2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于DECR2抗体的3篇模拟参考文献示例(注：文献为虚构，仅供示例参考)：
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1. **文献名称**：*DECR2 Antibody Validation in Lipid Metabolism Studies*
**作者**：Smith A, et al.
**摘要**：本研究验证了DECR2抗体的特异性，通过Western Blot和免疫组化证实其在人肝脏组织中的线粒体定位，并发现DECR2在非酒精性脂肪肝中的表达下调，提示其与脂质代谢紊乱相关。
2. **文献名称**：*Role of DECR2 in Prostate Cancer Progression Identified by Immunohistochemistry*
**作者**：Chen L, et al.
**摘要**：利用DECR2抗体进行免疫组化分析，发现DECR2在前列腺癌组织中高表达，且与肿瘤侵袭性和患者预后不良显著相关，提示其作为潜在生物标志物的价值。
3. **文献名称**：*DECR2 Knockout Mice Reveal Antioxidant Function via Antibody-Based Detection*
**作者**：Wang Y, et al.
**摘要**：通过构建DECR2基因敲除小鼠模型，结合特异性抗体检测，发现DECR2缺失导致活性氧(ROS)积累，证实其在氧化应激调控中的关键作用。
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如需真实文献，建议通过PubMed或Web of Science以“DECR2 antibody”或“DECR2 2.4-dienoyl-CoA reductase”为关键词检索。
DECR2 (2.4-Dienoyl-CoA Reductase 2) is a mitochondrial enzyme involved in the β-oxidation of polyunsaturated fatty acids (PUFAs). It catalyzes the reduction of 2.4-dienoyl-CoA to 3-enoyl-CoA, a critical step in metabolizing unsaturated fatty acids with double bonds at even-numbered positions. DECR2 is essential for maintaining energy homeostasis, particularly in tissues with high fatty acid oxidation demands, such as the heart and liver. Dysregulation of DECR2 has been linked to metabolic disorders, neurodegenerative diseases, and cancer, highlighting its role in cellular redox balance and lipid metabolism.
DECR2 antibodies are immunological tools developed to detect and quantify DECR2 protein expression in various experimental models. These antibodies are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to study DECR2's tissue distribution, subcellular localization, and expression changes under pathological conditions. Some antibodies target specific epitopes or post-translational modifications, enabling research into DECR2's functional regulation. Commercial DECR2 antibodies are often validated for specificity using knockout controls or siRNA-mediated silencing. Recent studies employ DECR2 antibodies to explore its involvement in oxidative stress, inflammation, and mitochondrial dysfunction, positioning it as a potential therapeutic target. However, antibody performance may vary depending on species reactivity, fixation methods, or sample preparation, necessitating careful optimization.
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