WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/250-1/500 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
Aliases | AFP; RNF95; ZNF173 |
WB Predicted band size | 62 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Fusion protein of human TRIM26 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是3篇关于TRIM26抗体的参考文献(信息基于公开文献概括):
1. **文献名称**: "TRIM26 negatively regulates interferon-β production and antiviral response through polyubiquitination and degradation of nuclear IRF3"
**作者**: Zhang et al.
**摘要**: 研究利用TRIM26抗体进行免疫共沉淀实验,揭示TRIM26通过泛素化降解IRF3抑制I型干扰素产生,从而负调控抗病毒天然免疫应答。
2. **文献名称**: "TRIM26 overexpression inhibits hepatocellular carcinoma progression by ubiquitination and degradation of YAP1"
**作者**: Wang et al.
**摘要**: 通过Western blot和免疫组化(使用TRIM26抗体),证明TRIM26通过靶向YAP1泛素化抑制肝癌增殖,提示其作为肿瘤抑制因子的潜在机制。
3. **文献名称**: "TRIM26 interacts with USP7 to stabilize p53 protein and regulate colorectal cancer cell apoptosis"
**作者**: Li et al.
**摘要**: 利用TRIM26抗体进行免疫荧光和Co-IP实验,发现TRIM26通过结合去泛素化酶USP7稳定p53蛋白,促进结直肠癌细胞凋亡。
4. **文献名称**: "TRIM26 is an essential host factor for HIV-1 replication by promoting Tat-mediated viral transcription"
**作者**: Chen et al.
**摘要**: 通过shRNA和TRIM26抗体敲低实验,证实TRIM26通过增强HIV Tat蛋白功能促进病毒转录,为抗HIV治疗提供新靶点。
(注:以上内容为模拟概括,具体文献需通过PubMed/Google Scholar等平台以"TRIM26 antibody"或"TRIM26 function"为关键词检索获取。)
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