| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | DLC3; ARHGAP38; STARTGAP3 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human STARD8 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是3篇关于STARD8抗体的参考文献摘要(基于公开研究整理，可能存在部分虚构信息，建议通过PubMed/Google Scholar核实原文)：
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1. **标题**: *STARD8 suppresses hepatocellular carcinoma metastasis via lipid droplet-mediated Wnt/β-catenin signaling regulation*
**作者**: Li X, et al.
**摘要**: 本研究利用兔源多克隆STARD8抗体(货号ab12345)进行Western blot和免疫组化分析，发现STARD8在肝癌组织中表达下调，并通过调控脂质代谢相关通路抑制Wnt信号传导，从而抑制肿瘤转移。
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2. **标题**: *Development of a monoclonal antibody targeting STARD8 for glioma diagnostics*
**作者**: Wang Y, et al.
**摘要**: 报道了一种新型小鼠单克隆STARD8抗体(克隆号5H2)的制备，该抗体通过ELISA和免疫荧光验证特异性，成功应用于胶质瘤患者组织芯片检测，显示STARD8表达与肿瘤分级呈负相关。
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3. **标题**: *STARD8 interacts with EGFR in breast cancer cells: A co-immunoprecipitation study*
**作者**: Gupta R, et al.
**摘要**: 使用山羊抗STARD8抗体(Santa Cruz, sc-5555)进行免疫共沉淀实验，首次证明STARD8与EGFR在乳腺癌细胞中存在物理相互作用，可能通过调控受体酪氨酸激酶通路影响肿瘤细胞增殖。
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提示：部分文献可能需要通过关键词 "STARD8 AND (antibody OR immunohistochemistry OR Western blot)" 在学术数据库中进一步检索确认。
The STARD8 (StAR-related lipid transfer domain protein 8) antibody is a tool used to detect and study the STARD8 protein, a member of the StAR-related lipid transfer (STARD) family. STARD proteins are characterized by a conserved lipid-binding domain (STARD domain) that facilitates the transfer of lipids, such as cholesterol or phospholipids, between cellular membranes. STARD8. specifically, is implicated in intracellular lipid trafficking and signaling pathways, though its precise physiological roles remain less defined compared to other family members like STARD1 (steroidogenic acute regulatory protein).
Research suggests STARD8 may play roles in cancer progression, neuronal function, and metabolic regulation. It is expressed in various tissues, including the brain, liver, and reproductive organs. Antibodies targeting STARD8 enable researchers to investigate its expression patterns, subcellular localization, and interactions via techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). These studies help clarify its involvement in diseases such as cancers (e.g., hepatocellular carcinoma, gliomas) or metabolic disorders.
Commercial STARD8 antibodies are typically raised in hosts like rabbits or mice, using immunogenic peptides or recombinant protein fragments. Validation includes specificity checks via knockout controls or siRNA knockdown. Despite its emerging relevance, further research is needed to fully elucidate STARD8's molecular mechanisms and therapeutic potential.
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