| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/20-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | FMNL; FHOD4; KW-13; C17orf1; C17orf1B |
| WB Predicted band size | 122 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human FMNL1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于FMNL1抗体的3篇参考文献示例(注：文献信息为模拟生成，仅供参考)：
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1. **文献名称**: *FMNL1 regulates actin cytoskeleton organization in cancer cell migration*
**作者**: Li X, et al.
**摘要**: 通过Western blot和免疫荧光(使用FMNL1抗体)发现，FMNL1通过调控肌动蛋白丝组装促进乳腺癌细胞迁移，沉默FMNL1可抑制侵袭表型。
2. **文献名称**: *Formin-like protein 1 (FMNL1) is overexpressed in Hodgkin lymphoma and mediates B-cell receptor signaling*
**作者**: Müller R, et al.
**摘要**: 利用FMNL1抗体进行免疫组化分析，证实FMNL1在霍奇金淋巴瘤中高表达，并参与B细胞受体信号通路的细胞骨架重组。
3. **文献名称**: *FMNL1-dependent cytoskeletal remodeling controls neutrophil extracellular trap formation*
**作者**: Clark K, et al.
**摘要**: 研究通过FMNL1抗体敲除实验，揭示FMNL1通过调节中性粒细胞骨架动态影响胞外诱捕网(NETs)的形成，影响先天免疫反应。
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**提示**：实际文献检索建议通过PubMed或Google Scholar搜索关键词“FMNL1 antibody” + “Western blot/immunohistochemistry”等实验方法，筛选目标研究。部分抗体公司(如Abcam、CST)官网也可能提供相关文献引用。
The FMNL1 (Formin-like 1) antibody is a tool used to study the function and expression of FMNL1. a member of the formin family of proteins involved in cytoskeletal regulation. FMNL1 plays a critical role in actin polymerization, a process essential for cell motility, cytokinesis, and intracellular trafficking. It is particularly implicated in immune cell function, cancer cell invasion, and endothelial barrier maintenance. Dysregulation of FMNL1 has been linked to pathologies such as cancer metastasis, chronic inflammation, and vascular disorders.
FMNL1 antibodies are designed to detect specific epitopes of the protein, enabling researchers to investigate its localization, expression levels, and interactions in various biological contexts. These antibodies are widely used in techniques like Western blotting, immunofluorescence, and immunohistochemistry. Monoclonal and polyclonal variants are available, each offering distinct advantages in specificity and sensitivity.
Research utilizing FMNL1 antibodies has shed light on its role in diseases. For example, elevated FMNL1 expression correlates with aggressive tumor behavior, suggesting its potential as a biomarker or therapeutic target. In immunology, FMNL1 modulates leukocyte migration, influencing inflammatory responses. Ongoing studies aim to clarify its molecular mechanisms and therapeutic relevance, driving demand for reliable antibodies to support basic and translational research.
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