Recombinant Human UROIIIS Protein，His

UROIIIS

The UROIIIS protein is a key catalyst in biochemical processes, specifically catalyzing the cyclization of hydroxymethyl bixane, a linear tetrapyrrole, to form macrocyclic uroporphyrinogen III. This enzymatic step serves as a critical branching point leading to various subpathways responsible for the synthesis of different porphyrins. UROIIIS Protein, Human (His) is the recombinant human-derived UROIIIS protein, expressed by E. coli , with C-6*His labeled tag.

SPR MST BLI ITC ELISA 细胞实验 药物筛选

Uroporphyrinogen-III Synthase; UROIIIS; UROS; Hydroxymethylbilane Hydrolyase [Cyclizing]; Uroporphyrinogen-III Cosynthase; UROS

Human

E. coli

C-6*His

Greater than 90% as determined by SDS-PAGE.

P10746

M1-C265

MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLIFTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCGNAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNLNSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVSCTAESPTPQALATGIRKALQPHGCC

Full Length

29 kDa

< 1.0 EU per μg protein as determined by the LAL method.

Freeze-dried powder

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

点位突变 标签定制 buffer定制 全长蛋白定制

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.