Mouse Monoclonal SLC7A3 Antibody

The SLC7A3 antibody is a tool used to detect the solute carrier family 7 member 3 (SLC7A3) protein, a cationic amino acid transporter part of the y+ system. SLC7A3 facilitates cellular uptake of arginine and other cationic amino acids, playing roles in nutrient sensing, cell proliferation, and immune function. This transmembrane protein is expressed in various tissues, including the liver, kidney, and immune cells, and has been implicated in pathologies like cancer and metabolic disorders. Antibodies targeting SLC7A3 enable researchers to study its expression patterns, subcellular localization, and regulatory mechanisms in both normal and diseased states. They are commonly used in techniques like Western blotting, immunohistochemistry, and immunofluorescence. Validated antibodies typically undergo specificity tests, such as knockout cell line controls, to confirm target recognition. Research involving SLC7A3 antibodies has explored its potential as a biomarker in tumors or its involvement in modulating nitric oxide synthesis pathways. Commercially available SLC7A3 antibodies are produced in various host species (e.g., rabbit, mouse) with distinct clonal properties. Selection depends on experimental needs, with emphasis on published validation data supporting applications in specific model systems. Ongoing studies aim to clarify its tissue-specific functions and therapeutic relevance.